GHRP-2 Reference
Educational, not medical advice reference for GHRP-2: GH Release; regulatory status, evidence posture, source review, and schedule notes. Also k…
Plain English
- What it is
- GHRP-2 (also called pralmorelin) is a lab-made peptide that signals the body to release more of its own growth hormone. It acts on the same body switch as ghrelin, the hormone that drives hunger.
- What people use it for
- In Japan it is approved only as a test to help check for growth hormone deficiency, not as a treatment. It is not an FDA-approved medicine in the US. People in gym and fitness circles talk about it for growth-hormone and appetite effects, but that is informal talk, not approved medical use.
- What the science shows
- Most human data come from using it as a quick test of growth hormone release, which supports its approved diagnostic role in Japan. In one small study of healthy men it raised growth hormone and made them eat more food, much like ghrelin. Long-term safety and benefit data are limited, and it can cause short-lived rises in the stress hormone cortisol.
- The catch
- GHRP-2 is not FDA-approved in the US, and US regulators flag it among bulk substances with safety concerns for pharmacy compounding. It is also banned in sport by the World Anti-Doping Agency at all times.
Reference summary
Clinical data exist primarily as GH-release provocative testing in adult and pediatric populations, supporting its Japanese diagnostic approval. Long-term therapeutic outcome data are limited.
Regulatory and posture
- Categories
- GH Release
- Aliases
- Pralmorelin, KP-102, GHRP2
- Evidence posture
- human - Approved only as a diagnostic in Japan; no US therapeutic approval. Long-term outcome data are limited.
- Regulatory status
- GHRP-2 (pralmorelin) is approved in Japan only as a diagnostic agent for GH deficiency. There is no FDA-approved GHRP-2 drug label in the US. FDA lists GHRP-2 among bulk drug substances with safety-risk concerns for compounding.
- Content review status
- research reference
Selected public sources
- FDA bulk drug substances with significant safety risks
- PubMed: Laferrère 2005 GHRP-2 increases food intake in healthy men (J Clin Endocrinol Metab)
Related tools
- Peptide reconstitution calculator - Convert vial mass and BAC water volume into mcg/ml.
- BAC water calculator - Solve BAC water volume for a target concentration.
- Multi-dose vial calculator - Estimate doses per vial and a projected vial-empty date.
- Reconstituted-vial storage window calculator - Estimate a generic usable-window date and days remaining.
- Peptide half-life calculator - Estimate single-dose decay from cited half-life constants.
- Injection-site rotation overview - Public overview of the Pro site-rotation planner.
For research and educational purposes only. Not medical advice.