RAD-140 Reference

Plain English

What it is

RAD-140, also called Testolone, is a SARM, which is a drug built to target the body's muscle-building hormone signals. It is sold only as a research chemical, not as an approved medicine, and no health agency has cleared it for people to use.

What people use it for

In bodybuilding and gym circles people talk about using it to add strength and lean muscle and to get a harder, more aggressive feel. That use is based on personal stories, not on any approved or proven use.

What the science shows

Most of what is known comes from lab and early testing. RAD-140 did reach one small, completed first-in-human safety trial in postmenopausal women with hormone-driven breast cancer, but it was never approved, and there are no human studies testing it for building muscle or losing fat.

The catch

The U.S. FDA has warned the public against SARMs, which are sold illegally and are often mislabeled, and world sport rules (WADA) ban them at all times as anabolic agents in class S1.2. Real reported harms include lowered natural testosterone, serious liver injury that can become severe, and worse cholesterol that can affect the heart. Some U.S. states have placed RAD-140 under their own Schedule III controlled-substance rules, though federal scheduling varies.

Reference summary

Phase 1 first-in-human oncology data in postmenopausal women with hormone-receptor-positive breast cancer exist; the trial excluded HER2-positive patients and did not advance to FDA approval. No body-composition human trials exist.

Regulatory and posture

Categories

SARM, Recovery

Aliases

Testolone, Non-steroidal SARM

Evidence posture

human - FDA enforcement attention. Sold only as a research chemical, not for human consumption per legal seller terms. WADA-prohibited under category S1.2 anabolic agents at all times, in and out of competition. No FDA-approved drug label and no human clinical efficacy program for body-composition use. Some US states have placed RAD-140 under Schedule III; possession without a prescription may be a state-level controlled-substance offense.

Regulatory status

No FDA-approved RAD-140 drug label. FDA has issued explicit consumer warnings against SARMs in bodybuilding products. WADA prohibits RAD-140 under category S1.2 anabolic agents at all times. Several US states have placed RAD-140 under state-level Schedule III provisions; federal scheduling status varies.

Content review status

research reference

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