S-101479 Reference

Plain English

What it is

S-101479 is a SARM, which is a lab-made drug that targets the body's muscle- and bone-building hormone signals. It was made as an experimental, bone-focused compound and is sold only as a research chemical, not as an approved medicine.

What people use it for

It does not have a real following in the bodybuilding or body-recomposition crowd. Any interest is mostly speculation about how it might work, not a proven or approved use for building muscle, losing fat, or treating bone loss.

What the science shows

The published research is all early lab work in animals and cells, mainly rats and bone cells. In female rats it raised bone mineral content without some side effects seen with other agents. There are no human trials, so any benefit for people has not been shown.

The catch

The FDA warns the public that SARMs are not approved, are illegally sold in bodybuilding products, and have been tied to serious harms like liver injury, heart attack, stroke, and lowered testosterone. The World Anti-Doping Agency bans all SARMs in sport at all times as S1.2 anabolic agents. For this compound there is no human safety data at all.

Reference summary

Published evidence is preclinical and mechanistic, focused on tissue-selective androgen-receptor activation. Human outcome data are absent.

Regulatory and posture

Categories

SARM, Bone

Aliases

S101479, Bone-selective SARM, Non-steroidal SARM

Evidence posture

preclinical - Preclinical tissue-selectivity work only. Human bone, muscle, or performance benefit has not been shown. WADA-prohibited; no FDA approval.

Regulatory status

No FDA-approved S-101479 drug label. FDA consumer warnings against SARMs sold in bodybuilding products apply to the class. WADA prohibits SARMs under category S1.2 anabolic agents at all times.

Content review status

research reference