For research and educational purposes only. Not medical advice.

hCG Reference

Educational, not medical advice reference for hCG: Reproductive, Hormonal; regulatory status, evidence posture, source review, and schedule note…

Reference summary

hCG is label-verified for fertility / hypogonadism uses. The Pregnyl and Novarel prescribing information anchors the approved indications, dosing ranges, and contraindications. Off-label use in men receiving testosterone therapy to maintain endogenous testicular function (Coviello 2005 J Clin Endocrinol Metab; subsequent Hsieh and Ramasamy work) is reflected in the urology literature but is outside the FDA label and requires prescriber oversight. pepSmart surfaces label-reference content only and explicitly does not endorse weight-loss hCG.

Regulatory and posture

Categories
Reproductive, Hormonal
Aliases
Human chorionic gonadotropin, Pregnyl, Novarel, Choriogonadotropin alfa, Ovidrel
Evidence posture
human - FDA-approved fertility / hypogonadism drug. FDA has issued public enforcement actions against hCG products marketed for weight loss; weight-loss use is outside the FDA label and is illegal to market in the US.
Regulatory status
FDA-approved prescription medication (Pregnyl, Novarel, and recombinant choriogonadotropin alfa as Ovidrel). Indicated for select fertility uses (induction of ovulation in anovulatory infertility as part of an assisted-reproduction protocol, treatment of selected hypogonadotropic hypogonadism in males, and prepubertal cryptorchidism not due to anatomic obstruction). FDA has issued explicit consumer warnings against hCG products marketed for weight loss; weight-loss use is not an FDA-approved indication and is illegal to market in the US. WADA prohibits hCG and LH and their releasing factors in males at all times under category S2.
Content review status
label verified

Selected public sources

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