For research and educational purposes only. Not medical advice.
MOTS-c Reference
Educational, not medical advice reference for MOTS-c: Longevity, Metabolic; regulatory status, evidence posture, source review, and schedule notes. Also know…
Reference summary
Published work includes rodent metabolic-homeostasis and insulin-sensitivity studies plus a small human PK/PD description. Direct human outcome evidence beyond PK is limited.
- Categories
- Longevity, Metabolic
- Aliases
- Mitochondrial open reading frame of 12S rRNA type-c, Mitochondrial-derived peptide
- Evidence posture
- translational — Mostly rodent metabolic data. Human evidence is limited to small PK/PD descriptions.
- Regulatory status
- No FDA-approved MOTS-c drug label. MOTS-c is a mitochondrial-derived peptide encoded in the mitochondrial 12S rRNA gene and is studied in rodent metabolic and skeletal-muscle models.
- Content review status
- research reference